American Statistical Association
A recent study has shown prediction concordance of five breast-cancer gene-signatures despite minimal overlap of the component genes. We studied the similarity of these gene-signatures on the basis of the enriched functional “modules” including metabolic and signaling pathways and a set of literature-defined concepts. Common “oncogenic” attributes were identified by intersecting the top-ranking pathways overrepresented in these signatures. The significance of such overlap was assessed using a resampling-based procedure.
|Date:||Wednesday, January 16, 2008|
|Time:||4:00 P.M. - 5:00 P.M.|
Memorial Sloan-Kettering Cancer Center
Department of Epidemiology and Biostatistics
307 East 63rd Street
(between First and Second Avenues)
3rd Floor Conference Room
New York, New York
Note: To gain access to the building, please follow the directions by the telephone in the foyer.