American Statistical Association
Serial tumor measurements are frequently used to assess whether cancer patients have responded to a therapeutic agent. Imprecise tumor measurements have the potential to cause erroneous conclusions in clinical trials studying new therapies and to lead to incorrect decisions in individual patient management. Repeatability and reproducibility are two standard measures of precision. There are no widely-accepted statistics, however, for quantifying either repeatability or reproducibility. In this talk, we will review methods that have been used in the radiology literature to evaluate the repeatability and reproducibility of tumor measurements. Following this review we will explore some additional methods that may be useful for this purpose. The methods will be illustrated using data prospectively collected on 32 patients with non-small cell lung cancer who agreed to undergo a repeat CT scan for research purposes.
|Date:||Wednesday, January 28, 2009|
|Time:||4:00 P.M. - 5:00 P.M.|
Memorial Sloan-Kettering Cancer Center
Department of Epidemiology and Biostatistics
307 East 63rd Street
(between First and Second Avenues)
3rd Floor Conference Room
New York, New York
Note: To gain access to the building, please follow the directions by the telephone in the foyer.