American Statistical Association New York City Metropolitan Area Chapter Memorial Sloan-Kettering Cancer Center Biostatistics Seminar

The National Polyp Study (NPS) demonstrated that colonoscopic polypectomy markedly reduced expected colorectal cancer (CRC) incidence. A more definitive indicator of the success of colonoscopic intervention would be a reduction of both incidence and mortality. Long-term mortality follow-up (FU) of the NPS was obtained through a match of the NPS cohort with that of the death certificate records of the National Death Index (NDI). The colorectal cancer mortality risk for the adenoma patients is compared internally with patients with only non-adenomatous polyps (hypothetically a low-risk group) and patients with malignant polyps (hypothetically a high-risk group). Also, an external comparison to the general population rates is given for those 10 or more years after their initial polypectomy. The preliminary results of this analysis will be presented.