American Statistical Association
The presentation will discuss how the real-world data (RWD) available from the healthcare system, such as health insurance data and electronic medical records, can be used to characterize use of medical treatments and make decisions about the choices of medical treatments that best advance public health. It will present a short introduction to the sources of RWD and the use of RWD in research, and will present a framework for using RWD in a way that yields meaningful and valid results. It will also discuss cases where results from RWD-based studies can be used to supplement or take the place of randomized trials. The presentation will share examples of decision-making using a variety of "big data" sources, and will demonstrate both the concept and practice of quickly turning real-world data into quality evidence.
Jeremy A. Rassen, M.S., Sc.D. is a pharmacoepidemiologist with nearly 25 years of academic and industry experience. He is Co-Founder, President and Chief Scientific Officer at Aetion, Inc., a healthcare technology company that provides science-driven real-world evidence (RWE) solutions to healthcare companies, regulatory bodies and academic centers. Dr. Rassen leads Aetion's efforts to design, scale and communicate scientific methodologies for obtaining valid and timely medical evidence from real-world data. Prior to Aetion, Dr. Rassen was an assistant professor at Harvard Medical School, where he focused on methods for improving the quality and validity of studies based on real-world data, including administrative claims and electronic health records. In peer-reviewed publications and invited talks in the United States, Europe and Asia, he has looked at how real-world data can be used to validly, transparently and reproducibly measure the safety, effectiveness and value of medications and other treatments. Before coming to Harvard, Dr. Rassen worked in Silicon Valley in a variety technology companies, including Hewlett-Packard and Epiphany, Inc. His focus was on high-performance software for the creation and analysis of large databases. Dr. Rassen received his bachelor's degree in Computer Science from Harvard College and his masters and doctorate degrees in Epidemiology from the Harvard T.H. Chan School of Public Health.